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Montelukast: Phenobarbital increases the blood concentration of Montelukast by about 40%. Rifampin may have the same effect. Therefore, the dose of Montelukast may need to be reduced when given concurrently with these drugs.
Levocetirizine: some interactions are less likely with cetirizine than with non-sedating antihistamines such as astemizole and terfenadine, since cetirizine appears to have low hepatic metabolism and little arrhythmogenic potential.
